Therapeutic Area·DG Japan

Neurology

Neurodegenerative disease cohorts (Alzheimer's, Parkinson's), epilepsy, multiple sclerosis. CSF and imaging biomarker programs aligned with ADNI and PPMI standards.

Steward · Anatomy · head

Avg. quality

Assets

Total rows

206,613

Certified

/ 5

Source systems

Source systemsMedidata Rave ClinicalRoche ElecsysCDP Imaging RepositoryTHREAD eDiary

Common tagsalzheimers · 3biomarker · 2cognitive · 1assessment · 1csf · 1imaging · 1mri · 1volumetrics · 1

Assets

Asset

Type · Status

Rows

Quality

Updated

MMSE Cognitive Assessment
Confidential
rave_qs_mmse
Mini-Mental State Examination (MMSE-2) scores collected at scheduled visits in Alzheimer's disease cohorts (AD-EARLY-201 and MCI-302).
TableApproved
24.1K
95
20d ago
CSF Alzheimer's Biomarker Panel
Confidential
bmkr_csf_ad_panel
Cerebrospinal fluid biomarkers (Aβ42, Aβ40, t-tau, p-tau181, p-tau217) measured on Roche Elecsys and Lumipulse platforms. Aligned with NIA-AA 2024 framework.
TableApproved
8.4K
87
24d ago
Brain Volumetric Features (FreeSurfer)
Restricted
img_brain_volumetrics
Hippocampal subfield volumes and whole-brain volumetric measurements derived from the FreeSurfer 7.4 pipeline. Includes Boundary Shift Integral (BSI) for longitudinal change.
TableApproved
31.2K
89
21d ago
Epilepsy Seizure Diary (ePRO)
Confidential
epro_seizure_diary
Patient-reported seizure events with ILAE 2017 type classification and trigger annotations. Captured via THREAD eDiary in EPILEPSY-203 study.
TableUnder Review
142.9K
73
17d ago
Amyloid Status (NIA-AA)
Internal
term_amyloid_status
Amyloid positivity definition per NIA-AA 2024 ATN framework. Source can be CSF Aβ42/40 ratio or amyloid PET (Centiloid ≥ 24).
Business TermApproved
—
100
4mo ago